nuri77Generation of MCK-Nur77 mice and animal husbandry. The murine Nur77 coding sequence was PCR amplified and cloned into the EcoRI site of the pCK4800 plasmid (gift of Eric Olson).TheIntroduction: The orphan nuclear receptor Nur77 (also known as NR4A1, NGFIB, TR3, TIS1, NAK-1, or N10) is a unique transcription factor encoded by an immediate early gene. Nur77